Cargando…
X-ray refinement significantly underestimates the level of microscopic heterogeneity in biomolecular crystals
Biomolecular X-ray structures typically provide a static, time- and ensemble-averaged view of molecular ensembles in crystals. In the absence of rigid-body motions and lattice defects, B-factors are thought to accurately reflect the structural heterogeneity of such ensembles. In order to study the e...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926004/ https://www.ncbi.nlm.nih.gov/pubmed/24504120 http://dx.doi.org/10.1038/ncomms4220 |