Lactate-mediated glia-neuronal signalling in the mammalian brain

Astrocytes produce and release L-lactate as a potential source of energy for neurons. Here we present evidence that L-lactate, independently of its caloric value, serves as an astrocytic signalling molecule in the locus coeruleus (LC). The LC is the principal source of norepinephrine to the frontal...

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Detalles Bibliográficos
Autores principales: Tang, F., Lane, S., Korsak, A., Paton, J. F. R., Gourine, A. V., Kasparov, S., Teschemacher, A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926012/
https://www.ncbi.nlm.nih.gov/pubmed/24518663
http://dx.doi.org/10.1038/ncomms4284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926012/
https://www.ncbi.nlm.nih.gov/pubmed/24518663
http://dx.doi.org/10.1038/ncomms4284

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