Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6

The mechanism by which acetaminophen (APAP) causes liver damage evokes many aspects drug metabolism, oxidative chemistry, and genetic-predisposition. In this study, we leverage the relative resistance of female C57BL/6 mice to APAP-induced liver damage (AILD) compared to male C57BL/6 mice in order t...

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Detalles Bibliográficos
Autores principales: Mohar, Isaac, Stamper, Brendan D., Rademacher, Peter M., White, Collin C., Nelson, Sidney D., Kavanagh, Terrance J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926121/
https://www.ncbi.nlm.nih.gov/pubmed/24563856
http://dx.doi.org/10.1016/j.redox.2014.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926121/
https://www.ncbi.nlm.nih.gov/pubmed/24563856
http://dx.doi.org/10.1016/j.redox.2014.01.008

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