Cargando…

Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6

The mechanism by which acetaminophen (APAP) causes liver damage evokes many aspects drug metabolism, oxidative chemistry, and genetic-predisposition. In this study, we leverage the relative resistance of female C57BL/6 mice to APAP-induced liver damage (AILD) compared to male C57BL/6 mice in order t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mohar, Isaac, Stamper, Brendan D., Rademacher, Peter M., White, Collin C., Nelson, Sidney D., Kavanagh, Terrance J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926121/ https://www.ncbi.nlm.nih.gov/pubmed/24563856 http://dx.doi.org/10.1016/j.redox.2014.01.008

Ejemplares similares

Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer
por: Kyriakides, Michael, et al.
Publicado: (2016)

p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo
por: Stamper, Brendan D, et al.
Publicado: (2015)

Acetaminophen Protein Adducts in Hospitalized Children Receiving Multiple Doses of Acetaminophen
por: Jiang, Sibo, et al.
Publicado: (2019)

Peroxiredoxin 3 Inhibits Acetaminophen-Induced Liver Pyroptosis Through the Regulation of Mitochondrial ROS
por: Wang, Yue, et al.
Publicado: (2021)

Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity
por: James, Laura, et al.
Publicado: (2015)

Peroxiredoxin 6 mediates acetaminophen-induced hepatocyte death through JNK activation
por: Lee, Dong Hun, et al.
Publicado: (2020)

Acetaminophen-cysteine adducts during therapeutic dosing and following overdose
por: Heard, Kennon J, et al.
Publicado: (2011)

Peroxiredoxin 6 attenuates ischemia- and hypoxia-induced liver damage of brain-dead donors
por: TU, QIANG, et al.
Publicado: (2016)

Simple Reversed-Phase HPLC Method with Spectrophotometric Detection for Measuring Acetaminophen-Protein Adducts in Rat Liver Samples
por: Acharya, Miteshkumar, et al.
Publicado: (2012)

Human Ex-Vivo Liver Model for Acetaminophen-induced Liver Damage
por: Schreiter, Thomas, et al.
Publicado: (2016)

Behavioral Characterization of GCLM-Knockout Mice, a Model for Enhanced Susceptibility to Oxidative Stress
por: Cole, Toby B., et al.
Publicado: (2011)

Data on expression of lipoxygenases-5 and -12 in the normal and acetaminophen-damaged liver
por: Suciu, Maria, et al.
Publicado: (2016)

Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice
por: Mohamad, Nurul Elyani, et al.
Publicado: (2018)

Kaempferol suppresses acetaminophen-induced liver damage by upregulation/activation of SIRT1
por: BinMowyna, Mona Nasser, et al.
Publicado: (2021)

Antioxidants Special Issue: Peroxiredoxin 6 as a Unique Member of the Peroxiredoxin Family
por: Fisher, Aron B.
Publicado: (2019)

Peroxiredoxin V Protects against UVB-Induced Damage of Keratinocytes
por: Kim, Sin Ri, et al.
Publicado: (2023)

Fortilin potentiates the peroxidase activity of Peroxiredoxin-1 and protects against alcohol-induced liver damage in mice
por: Chattopadhyay, Abhijnan, et al.
Publicado: (2016)

Peroxiredoxin 6 in skin carcinogenesis
por: Rolfs, Frank, et al.
Publicado: (2014)

Peroxiredoxin6 in Endothelial Signaling
por: Patel, Priyal, et al.
Publicado: (2019)

Radioprotective Role of Peroxiredoxin 6
por: Sharapov, Mars G., et al.
Publicado: (2019)

Intranasal Acetaminophen Abuse and Nasal, Pharyngeal, and Laryngotracheal Damage
por: Lin, Yufan, et al.
Publicado: (2019)

Neuroprotective effect of peroxiredoxin 6 against hypoxia-induced retinal ganglion cell damage
por: Tulsawani, Rajkumar, et al.
Publicado: (2010)

The role of peroxiredoxins in cancer
por: Nicolussi, Arianna, et al.
Publicado: (2017)

Distribution and Features of the Six Classes of Peroxiredoxins
por: Poole, Leslie B., et al.
Publicado: (2016)

Peroxynitrite and Peroxiredoxin in the Pathogenesis of Experimental Amebic Liver Abscess
por: Pacheco-Yepez, Judith, et al.
Publicado: (2014)

Acetaldehyde adducts in alcoholic liver disease
por: Setshedi, Mashiko, et al.
Publicado: (2010)

The Role of Thioredoxin/Peroxiredoxin in the β-Cell Defense Against Oxidative Damage
por: Stancill, Jennifer S., et al.
Publicado: (2021)

Overview on Peroxiredoxin
por: Rhee, Sue Goo
Publicado: (2016)

Inhibition of the phospholipase A(2) activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia
por: Benipal, Bavneet, et al.
Publicado: (2015)

Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice
por: Ozkosem, Burak, et al.
Publicado: (2015)

The Role of Peroxiredoxin 6 in Cell Signaling
por: Arevalo, José A., et al.
Publicado: (2018)

Peroxiredoxin 6: The Protector of Male Fertility
por: O’Flaherty, Cristian
Publicado: (2018)

NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice
por: Murray, Thomas V.A., et al.
Publicado: (2015)

PREX: PeroxiRedoxin classification indEX, a database of subfamily assignments across the diverse peroxiredoxin family
por: Soito, Laura, et al.
Publicado: (2011)

Gender Difference on the Effect of Omega-3 Polyunsaturated Fatty Acids on Acetaminophen-Induced Acute Liver Failure
por: Liu, Yunzhi, et al.
Publicado: (2020)

Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage
por: Badmann, A, et al.
Publicado: (2011)

Antioxidant and Hepatoprotective Properties of Tofu (Curdle Soymilk) against Acetaminophen-Induced Liver Damage in Rats
por: Yakubu, Ndatsu, et al.
Publicado: (2013)

Acrolein scavengers, cysteamine and N-benzylhydroxylamine, reduces the mouse liver damage after acetaminophen overdose
por: KOYAMA, Ryo, et al.
Publicado: (2016)

Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice
por: Naim, Samara, et al.
Publicado: (2021)

Acetaminophen: A Liver Killer or Thriller
por: Zacharia, George S, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_uvgcio50lb8f40holpidtu3s87