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Thapsigargin Induces Apoptosis by Impairing Cytoskeleton Dynamics in Human Lung Adenocarcinoma Cells

The objective of this study was performed to investigate the effects of thapsigargin on apoptosis, actin cytoskeletal dynamics, and actin cytoskeletal proteins in human lung adenocarcinoma cell. Thapsigargin is a specific irreversible inhibitor of ER calcium-ATPase, which may promote ER stress by de...

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Detalles Bibliográficos
Autores principales: Wang, Fei, Liu, Da-zhong, Xu, Hao, Li, Yi, Wang, Wei, Liu, Bai-lu, Zhang, Lin-you
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926280/
https://www.ncbi.nlm.nih.gov/pubmed/24605059
http://dx.doi.org/10.1155/2014/619050