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Laboratory divergence of Methylobacterium extorquens AM1 through unintended domestication and past selection for antibiotic resistance

BACKGROUND: A common assumption of microorganisms is that laboratory stocks will remain genetically and phenotypically constant over time, and across laboratories. It is becoming increasingly clear, however, that mutations can ruin strain integrity and drive the divergence or “domestication” of stoc...

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Detalles Bibliográficos
Autores principales: Carroll, Sean Michael, Xue, Katherine S, Marx, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926354/
https://www.ncbi.nlm.nih.gov/pubmed/24384040
http://dx.doi.org/10.1186/1471-2180-14-2