PDGF-induced PI3K-mediated signaling enhances the TGF-β-induced osteogenic differentiation of human mesenchymal stem cells in a TGF-β-activated MEK-dependent manner

Transforming growth factor-β (TGF-β) is a critical regulator of osteogenic differentiation and the platelet-derived growth factor (PDGF) is a chemoattractant or mitogen of osteogenic mesenchymal cells. However, the combined effects of these regulators on the osteogenic differentiation of mesenchymal...

Descripción completa

Detalles Bibliográficos
Autores principales: YOKOTA, JUN, CHOSA, NAOYUKI, SAWADA, SHUNSUKE, OKUBO, NAOTO, TAKAHASHI, NORIKO, HASEGAWA, TOMOKAZU, KONDO, HISATOMO, ISHISAKI, AKIRA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926498/
https://www.ncbi.nlm.nih.gov/pubmed/24378341
http://dx.doi.org/10.3892/ijmm.2013.1606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926498/
https://www.ncbi.nlm.nih.gov/pubmed/24378341
http://dx.doi.org/10.3892/ijmm.2013.1606

Ejemplares similares