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Development of an Antigen-DNAzyme Based Probe for a Direct Antibody-Antigen Assay Using the Intrinsic DNAzyme Activity of a Daunomycin Aptamer

G-Quadruplex (G-4) structures are formed when G-rich DNA sequences fold into intra- or intermolecular four-stranded structures in the presence of metal ions. G-4-hemin complexes are often effective peroxidase-mimicking DNAzymes that are applied in many detection systems. This work reports the applic...

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Detalles Bibliográficos
Autores principales: Omar, Noorsharmimi, Loh, Qiuting, Tye, Gee Jun, Choong, Yee Siew, Noordin, Rahmah, Glökler, Jörn, Lim, Theam Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926560/
https://www.ncbi.nlm.nih.gov/pubmed/24379042
http://dx.doi.org/10.3390/s140100346