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Ten-year follow-up of a prospective trial for the targeted therapy of gastric cancer with the human monoclonal antibody PAT-SC1

The fully human monoclonal antibody PAT-SC1 is specific for an isoform of CD55 (decay-accelerating factor) designated CD55(PAT-SC1). This antigen is expressed in the majority (80%) of gastric cancers (GCs), and the antibody induces tumour cell-specific apoptosis in vitro as well as in vivo. PAT-SC1,...

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Detalles Bibliográficos
Autores principales: HENSEL, FRANK, TIMMERMANN, WOLFGANG, VON RAHDEN, BURKHARD H.A., ROSENWALD, ANDREAS, BRÄNDLEIN, STEPHANIE, ILLERT, BERTRAM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926647/
https://www.ncbi.nlm.nih.gov/pubmed/24452482
http://dx.doi.org/10.3892/or.2014.2987