Analysis of the B-RAF(V600E) mutation in cutaneous melanoma patients with occupational sun exposure

Sun-exposure is one of the risk factors associated with the development of a cutaneous neoplasm. In melanoma, the Ras-Raf-MEK-ERK (MAPK) signaling pathway is constitutively activated through multiple mechanisms, including B-RAF mutation. It has been hypothesized that B-RAF mutations in melanocytic l...

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Detalles Bibliográficos
Autores principales: CANDIDO, SAVERIO, RAPISARDA, VENERANDO, MARCONI, ANDREA, MALAPONTE, GRAZIA, BEVELACQUA, VALENTINA, GANGEMI, PIETRO, SCALISI, AURORA, McCUBREY, JAMES A., MAESTRO, ROBERTA, SPANDIDOS, DEMETRIOS A., FENGA, CONCETTINA, LIBRA, MASSIMO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926654/
https://www.ncbi.nlm.nih.gov/pubmed/24424406
http://dx.doi.org/10.3892/or.2014.2977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926654/
https://www.ncbi.nlm.nih.gov/pubmed/24424406
http://dx.doi.org/10.3892/or.2014.2977

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