Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell Carcinoma

The pathogenesis of BCC is associated with sonic hedgehog (SHH) signaling. Vismodegib, a smoothened inhibitor that targets this pathway, is now in clinical use for advanced BCC patients, but its efficacy is limited. Therefore, new therapeutic options for this cancer are required. We studied gene exp...

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Detalles Bibliográficos
Autores principales: Ning, Hanna, Mitsui, Hiroshi, Wang, Claire Q.F., Suárez-Fariñas, Mayte, Gonzalez, Juana, Shah, Kejal R., Chen, Jie, Coats, Israel, Felsen, Diane, Carucci, John A., Krueger, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926823/
https://www.ncbi.nlm.nih.gov/pubmed/24163262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926823/
https://www.ncbi.nlm.nih.gov/pubmed/24163262

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