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Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5

Kinesin motor proteins exert essential cellular functions in all eukaryotes. They control mitosis, migration and intracellular transport through interaction with microtubules. Small molecule inhibitors of the mitotic kinesin KiF11/Eg5 are a promising new class of anti-neoplastic agents currently eva...

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Detalles Bibliográficos
Autores principales: Exertier, Prisca, Javerzat, Sophie, Wang, Baigang, Franco, Mélanie, Herbert, John, Platonova, Natalia, Winandy, Marie, Pujol, Nadège, Nivelles, Olivier, Ormenese, Sandra, Godard, Virginie, Becker, Jürgen, Bicknell, Roy, Pineau, Raphael, Wilting, Jörg, Bikfalvi, Andreas, Hagedorn, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926828/
https://www.ncbi.nlm.nih.gov/pubmed/24327603