In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics

Current assays for somatic mutation analysis are based on extracts from tissue sections that often contain morphologically heterogeneous neoplastic regions with variable contents of genetically normal stromal and inflammatory cells, obscuring the results of the assays. We have developed an RNA-based...

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Detalles Bibliográficos
Autores principales: Grundberg, Ida, Kiflemariam, Sara, Mignardi, Marco, Imgenberg-Kreuz, Juliana, Edlund, Karolina, Micke, Patrick, Sundström, Magnus, Sjöblom, Tobias, Botling, Johan, Nilsson, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926836/
https://www.ncbi.nlm.nih.gov/pubmed/24280411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926836/
https://www.ncbi.nlm.nih.gov/pubmed/24280411

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