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In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics
Current assays for somatic mutation analysis are based on extracts from tissue sections that often contain morphologically heterogeneous neoplastic regions with variable contents of genetically normal stromal and inflammatory cells, obscuring the results of the assays. We have developed an RNA-based...
Autores principales: | Grundberg, Ida, Kiflemariam, Sara, Mignardi, Marco, Imgenberg-Kreuz, Juliana, Edlund, Karolina, Micke, Patrick, Sundström, Magnus, Sjöblom, Tobias, Botling, Johan, Nilsson, Mats |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926836/ https://www.ncbi.nlm.nih.gov/pubmed/24280411 |
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