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The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer

EZH2, a core member of the Polycomb Repressor Complex 2 (PRC2), mediates transcriptional silencing by catalyzing the trimethylation of histone 3 lysine 27 (H3K27), which plays key roles in cancer initiation and progression. Here, we investigated the expression pattern and biological roles of EZH2 in...

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Detalles Bibliográficos
Autores principales: Li, Zhongwu, Wang, Yanling, Qiu, Jing, Li, Qiang, Yuan, Chunping, Zhang, Wei, Wang, Dongmiao, Ye, Jinhai, Jiang, Hongbin, Yang, Jianrong, Cheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926847/
https://www.ncbi.nlm.nih.gov/pubmed/24345883