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Resistance to Dasatinib in primary chronic lymphocytic leukemia lymphocytes involves AMPK-mediated energetic re-programming

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults in the western world. Although promising new therapies for this incurable disease are being tested in clinical trials, the therapeutic relevance of metabolic rewiring in chronic lymphocytic leukemia (CLL) is poorly understood....

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Detalles Bibliográficos
Autores principales: Marignac, Veronica Martinez, Smith, Sarah, Toban, Nader, Bazile, Miguel, Aloyz, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926848/
https://www.ncbi.nlm.nih.gov/pubmed/24334291