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Wnt/β-catenin pathway as a potential prognostic and predictive marker in patients with advanced ovarian cancer

BACKGROUND: β-catenin is the key protein in the WNT signalling pathway and it forms adherent junctions together with E-cadherin. In ovarian carcinoma, abnormal expression of β-catenin, E-cadherin and WNT-1 was observed, but their prognostic and predictive role is unclear. The aim of this study was t...

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Detalles Bibliográficos
Autores principales: Bodnar, Lubomir, Stanczak, Aleksandra, Cierniak, Szczepan, Smoter, Marta, Cichowicz, Marzena, Kozlowski, Wojciech, Szczylik, Cezary, Wieczorek, Maciej, Lamparska-Przybysz, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926861/
https://www.ncbi.nlm.nih.gov/pubmed/24499657
http://dx.doi.org/10.1186/1757-2215-7-16