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Arsenic in leukemia: A RSKy business

It has been known for many years that arsenic trioxide (As(2)O(3); ATO) is an effective therapy for acute promyelocytic leukemia but has little activity against other forms of the disease. ATO has diverse modes of action, but is well known to generate high levels of reactive oxygen species in cells...

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Detalles Bibliográficos
Autor principal: Dent, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926878/
https://www.ncbi.nlm.nih.gov/pubmed/24025257
http://dx.doi.org/10.4161/cbt.26159