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Protecting the proteome: Eukaryotic cotranslational quality control pathways

The correct decoding of messenger RNAs (mRNAs) into proteins is an essential cellular task. The translational process is monitored by several quality control (QC) mechanisms that recognize defective translation complexes in which ribosomes are stalled on substrate mRNAs. Stalled translation complexe...

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Detalles Bibliográficos
Autores principales: Lykke-Andersen, Jens, Bennett, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926952/
https://www.ncbi.nlm.nih.gov/pubmed/24535822
http://dx.doi.org/10.1083/jcb.201311103