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Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1

The aim of this work was to assess the role of ethanol-derived acetate and acetate-mediated histone acetylation in arachidonic acid-induced stress in HepG2 cells and cells overexpressing CYP2E1. Cells were grown for 7 days with 1 mM sodium acetate or 100 mM ethanol; their acetylated histone proteins...

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Detalles Bibliográficos
Autores principales: Holownia, A., Mroz, R. M., Wielgat, P., Jakubow, P., Jablonski, J., Sulek, J., Braszko, J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927057/
https://www.ncbi.nlm.nih.gov/pubmed/24287576
http://dx.doi.org/10.1007/s00210-013-0942-4