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Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1
The aim of this work was to assess the role of ethanol-derived acetate and acetate-mediated histone acetylation in arachidonic acid-induced stress in HepG2 cells and cells overexpressing CYP2E1. Cells were grown for 7 days with 1 mM sodium acetate or 100 mM ethanol; their acetylated histone proteins...
Autores principales: | Holownia, A., Mroz, R. M., Wielgat, P., Jakubow, P., Jablonski, J., Sulek, J., Braszko, J. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927057/ https://www.ncbi.nlm.nih.gov/pubmed/24287576 http://dx.doi.org/10.1007/s00210-013-0942-4 |
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