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Insights into the binding of GABA to the insect RDL receptor from atomistic simulations: a comparison of models

The resistance to dieldrin (RDL) receptor is an insect pentameric ligand-gated ion channel (pLGIC). It is activated by the neurotransmitter γ-aminobutyric acid (GABA) binding to its extracellular domain; hence elucidating the atomistic details of this interaction is important for understanding how t...

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Detalles Bibliográficos
Autores principales: Comitani, Federico, Cohen, Netta, Ashby, Jamie, Botten, Dominic, Lummis, Sarah C. R., Molteni, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927061/
https://www.ncbi.nlm.nih.gov/pubmed/24442887
http://dx.doi.org/10.1007/s10822-013-9704-0