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Insights into the binding of GABA to the insect RDL receptor from atomistic simulations: a comparison of models
The resistance to dieldrin (RDL) receptor is an insect pentameric ligand-gated ion channel (pLGIC). It is activated by the neurotransmitter γ-aminobutyric acid (GABA) binding to its extracellular domain; hence elucidating the atomistic details of this interaction is important for understanding how t...
Autores principales: | Comitani, Federico, Cohen, Netta, Ashby, Jamie, Botten, Dominic, Lummis, Sarah C. R., Molteni, Carla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927061/ https://www.ncbi.nlm.nih.gov/pubmed/24442887 http://dx.doi.org/10.1007/s10822-013-9704-0 |
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