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The missing story behind Genome Wide Association Studies: single nucleotide polymorphisms in gene deserts have a story to tell

Genome wide association studies are central to the evolution of personalized medicine. However, the propensity for single nucleotide polymorphisms (SNPs) to fall outside of genes means that understanding how these polymorphisms alter cellular function requires an expanded view of human genetics. Int...

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Detalles Bibliográficos
Autores principales: Schierding, William, Cutfield, Wayne S., O'Sullivan, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927098/
https://www.ncbi.nlm.nih.gov/pubmed/24600475
http://dx.doi.org/10.3389/fgene.2014.00039