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TNF Receptor-Associated Factor 1 is a Major Target of Soluble TWEAK

Soluble tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK), in contrast to membrane TWEAK and TNF, is only a weak activator of the classical NFκB pathway. We observed that soluble TWEAK was regularly more potent than TNF with respect to the induction of TNF receptor-associated factor...

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Detalles Bibliográficos
Autores principales: Carmona Arana, José Antonio, Seher, Axel, Neumann, Manfred, Lang, Isabell, Siegmund, Daniela, Wajant, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927163/
https://www.ncbi.nlm.nih.gov/pubmed/24600451
http://dx.doi.org/10.3389/fimmu.2014.00063