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Subcellular glucose exposure biases the spatial distribution of insulin granules in single pancreatic beta cells

In living tissues, a cell is exposed to chemical substances delivered partially to its surface. Such a heterogeneous chemical environment potentially induces cell polarity. To evaluate this effect, we developed a microfluidic device that realizes spatially confined delivery of chemical substances at...

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Detalles Bibliográficos
Autores principales:	Terao, Kyohei, Gel, Murat, Okonogi, Atsuhito, Fuke, Ariko, Okitsu, Teru, Tada, Takashi, Suzuki, Takaaki, Nagamatsu, Shinya, Washizu, Masao, Kotera, Hidetoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927211/ https://www.ncbi.nlm.nih.gov/pubmed/24535122 http://dx.doi.org/10.1038/srep04123

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