MT-7716, a novel selective nonpeptidergic NOP receptor agonist, effectively blocks ethanol-induced increase in GABAergic transmission in the rat central amygdala

The GABAergic system in the central amygdala (CeA) plays a major role in ethanol dependence and the anxiogenic-like response to ethanol withdrawal. A large body of evidence shows that Nociceptin/Orphanin FQ (N/OFQ) regulates ethanol intake and anxiety-like behavior. In the rat, ethanol significantly...

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Detalles Bibliográficos
Autores principales: Kallupi, Marsida, Oleata, Christopher S., Luu, George, Teshima, Koji, Ciccocioppo, Roberto, Roberto, Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927450/
https://www.ncbi.nlm.nih.gov/pubmed/24600360
http://dx.doi.org/10.3389/fnint.2014.00018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927450/
https://www.ncbi.nlm.nih.gov/pubmed/24600360
http://dx.doi.org/10.3389/fnint.2014.00018

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