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MT-7716, a novel selective nonpeptidergic NOP receptor agonist, effectively blocks ethanol-induced increase in GABAergic transmission in the rat central amygdala
The GABAergic system in the central amygdala (CeA) plays a major role in ethanol dependence and the anxiogenic-like response to ethanol withdrawal. A large body of evidence shows that Nociceptin/Orphanin FQ (N/OFQ) regulates ethanol intake and anxiety-like behavior. In the rat, ethanol significantly...
Autores principales: | Kallupi, Marsida, Oleata, Christopher S., Luu, George, Teshima, Koji, Ciccocioppo, Roberto, Roberto, Marisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927450/ https://www.ncbi.nlm.nih.gov/pubmed/24600360 http://dx.doi.org/10.3389/fnint.2014.00018 |
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