Synaptic protein dysregulation in myotonic dystrophy type 1: Disease neuropathogenesis beyond missplicing

The toxicity of expanded transcripts in myotonic dystrophy type 1 (DM1) is mainly mediated by the disruption of alternative splicing. However, the detailed disease mechanisms in the central nervous system (CNS) have not been fully elucidated. In our recent study, we demonstrated that the accumulatio...

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Detalles Bibliográficos
Autores principales: Hernández-Hernández, Oscar, Sicot, Géraldine, Dinca, Diana M., Huguet, Aline, Nicole, Annie, Buée, Luc, Munnich, Arnold, Sergeant, Nicolas, Gourdon, Geneviève, Gomes-Pereira, Mário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
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Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927487/
https://www.ncbi.nlm.nih.gov/pubmed/25003003
http://dx.doi.org/10.4161/rdis.25553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927487/
https://www.ncbi.nlm.nih.gov/pubmed/25003003
http://dx.doi.org/10.4161/rdis.25553

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