Redox-responsive targeted gelatin nanoparticles for delivery of combination wt-p53 expressing plasmid DNA and gemcitabine in the treatment of pancreatic cancer

BACKGROUND: Pancreatic adenocarcinoma is one of the most dreaded cancers with very low survival rate and poor prognosis to the existing frontline chemotherapeutic drugs. Gene therapy in combination with a cytotoxic agent could be a promising approach to circumvent the limitations of previously attem...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Singh, Amit, Amiji, Mansoor M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927583/
https://www.ncbi.nlm.nih.gov/pubmed/24507760
http://dx.doi.org/10.1186/1471-2407-14-75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927583/
https://www.ncbi.nlm.nih.gov/pubmed/24507760
http://dx.doi.org/10.1186/1471-2407-14-75

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