Cargando…

Redox-responsive targeted gelatin nanoparticles for delivery of combination wt-p53 expressing plasmid DNA and gemcitabine in the treatment of pancreatic cancer

BACKGROUND: Pancreatic adenocarcinoma is one of the most dreaded cancers with very low survival rate and poor prognosis to the existing frontline chemotherapeutic drugs. Gene therapy in combination with a cytotoxic agent could be a promising approach to circumvent the limitations of previously attem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Jing, Singh, Amit, Amiji, Mansoor M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927583/ https://www.ncbi.nlm.nih.gov/pubmed/24507760 http://dx.doi.org/10.1186/1471-2407-14-75

Ejemplares similares

Therapeutic Gene Delivery and Transfection in Human Pancreatic Cancer Cells using Epidermal Growth Factor Receptor-targeted Gelatin Nanoparticles
por: Xu, Jing, et al.
Publicado: (2012)

Modification of tumor cell exosome content by transfection with wt-p53 and microRNA-125b expressing plasmid DNA and its effect on macrophage polarization
por: Trivedi, M, et al.
Publicado: (2016)

Modulation of Macrophage Functional Polarity towards Anti-Inflammatory Phenotype with Plasmid DNA Delivery in CD44 Targeting Hyaluronic Acid Nanoparticles
por: Tran, Thanh-Huyen, et al.
Publicado: (2015)

Pancreatic Cancer Cell Exosome-Mediated Macrophage Reprogramming and the Role of MicroRNAs 155 and 125b2 Transfection using Nanoparticle Delivery Systems
por: Su, Mei-Ju, et al.
Publicado: (2016)

Gelatin-Based Electrospun Nanofibers Cross-Linked Using Horseradish Peroxidase for Plasmid DNA Delivery
por: Furuno, Kotoko, et al.
Publicado: (2022)

Wilms Tumor Gene (WT1) Peptide–based Cancer Vaccine Combined With Gemcitabine for Patients With Advanced Pancreatic Cancer
por: Nishida, Sumiyuki, et al.
Publicado: (2014)

Development of Peptide-Based Nanoparticles for Mitochondrial Plasmid DNA Delivery
por: Faria, Rúben, et al.
Publicado: (2021)

Ionizable Lipid Nanoparticle-Mediated Delivery of Plasmid DNA in Cardiomyocytes
por: Scalzo, Sérgio, et al.
Publicado: (2022)

Development and Characterization of Nanoparticles for the Delivery of Gemcitabine Hydrochloride
por: Khaira, Rekha, et al.
Publicado: (2014)

Redox-Sensitive Gelatin/Silica-Aptamer Nanogels for Targeted siRNA Delivery
por: Zhao, Xueqin, et al.
Publicado: (2019)

Preparation and Characterization of Cationic PLA-PEG Nanoparticles for Delivery of Plasmid DNA
por: Zou, Weiwei, et al.
Publicado: (2009)

Modulation of Chitosan-TPP Nanoparticle Properties for Plasmid DNA Vaccines Delivery
por: Nunes, Renato, et al.
Publicado: (2022)

Mesoporous Organosilica Nanoparticles with Tetrasulphide Bond to Enhance Plasmid DNA Delivery
por: Zhang, Yue, et al.
Publicado: (2023)

MicroRNA-34a Encapsulated in Hyaluronic Acid Nanoparticles Induces Epigenetic Changes with Altered Mitochondrial Bioenergetics and Apoptosis in Non-Small-Cell Lung Cancer Cells
por: Trivedi, Malav, et al.
Publicado: (2017)

Gold Nanoparticles sensitize pancreatic cancer cells to gemcitabine
por: Huai, Yanyan, et al.
Publicado: (2019)

Layered double hydroxide nanoparticles as cellular delivery vectors of supercoiled plasmid DNA
por: Xu, Zhi Ping, et al.
Publicado: (2007)

Delivery of Plasmid DNA by Ionizable Lipid Nanoparticles to Induce CAR Expression in T Cells
por: Prazeres, Pedro Henrique Dias Moura, et al.
Publicado: (2023)

Delivery of Gemcitabine Prodrugs Employing Mesoporous Silica Nanoparticles
por: Malfanti, Alessio, et al.
Publicado: (2016)

Mad2 Checkpoint Gene Silencing Using Epidermal Growth Factor Receptor-Targeted Chitosan Nanoparticles in Non-Small Cell Lung Cancer Model
por: Nascimento, Ana Vanessa, et al.
Publicado: (2014)

Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells
por: Bjånes, Tormod, et al.
Publicado: (2020)

Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53
por: Abrams, Stephen L., et al.
Publicado: (2022)

Therapeutic Efficacy and Safety of Paclitaxel/Lonidamine Loaded EGFR-Targeted Nanoparticles for the Treatment of Multi-Drug Resistant Cancer
por: Milane, Lara, et al.
Publicado: (2011)

Retraction Note to “In vitro transfection of plasmid DNA by different-cationized gelatin with or without ultrasound irradiation”
por: TABATA, Yasuhiko
Publicado: (2020)

Redox-responsive nanoplatform for codelivery of miR-519c and gemcitabine for pancreatic cancer therapy
por: Xin, Xiaofei, et al.
Publicado: (2020)

Double domain polyethylenimine-based nanoparticles for integrin receptor mediated delivery of plasmid DNA
por: Sadeghpour, Hossein, et al.
Publicado: (2018)

Co-assembled Ca(2+) Alginate-Sulfate Nanoparticles for Intracellular Plasmid DNA Delivery
por: Goldshtein, Matan, et al.
Publicado: (2019)

Electrosprayed Alginate Nanoparticles as CRISPR Plasmid DNA Delivery Carrier: Preparation, Optimization, and Characterization
por: Alallam, Batoul, et al.
Publicado: (2020)

Development and characterization of gelatin based nanoparticles for targeted delivery of zidovudine
por: Jadhav, Namdeo R, et al.
Publicado: (2013)

Gelatin Nanoparticles for Complexation and Enhanced Cellular Delivery of mRNA
por: Andrée, Lea, et al.
Publicado: (2022)

Surface functionalization of gold nanoparticles using hetero-bifunctional poly(ethylene glycol) spacer for intracellular tracking and delivery
por: Shenoy, Dinesh, et al.
Publicado: (2006)

Intracellular redox-responsive nanocarrier for plasmid delivery: in vitro characterization and in vivo studies in mice
por: Zhang, Lifen, et al.
Publicado: (2016)

MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer
por: Yang, Xiaoqian, et al.
Publicado: (2015)

Inhibition of hexokinase-2 with targeted liposomal 3-bromopyruvate in an ovarian tumor spheroid model of aerobic glycolysis
por: Gandham, Srujan Kumar, et al.
Publicado: (2015)

Enhancement of Pancreatic Cancer Therapy Efficacy by Type-1 Matrix Metalloproteinase-Functionalized Nanoparticles for the Selective Delivery of Gemcitabine and Erlotinib
por: Yin, Na, et al.
Publicado: (2020)

Local gene delivery via endovascular stents coated with dodecylated chitosan–plasmid DNA nanoparticles
por: Zhu, Dunwan, et al.
Publicado: (2010)

In Vitro Gene Delivery in Retinal Pigment Epithelium Cells by Plasmid DNA-Wrapped Gold Nanoparticles
por: Trigueros, Sònia, et al.
Publicado: (2019)

Modified Gold Nanoparticles to Overcome the Chemoresistance to Gemcitabine in Mutant p53 Cancer Cells
por: García-Garrido, Eduardo, et al.
Publicado: (2021)

Gemcitabine Combination Nano Therapies for Pancreatic Cancer
por: Samanta, Kamalika, et al.
Publicado: (2019)

MicroRNA-223 Induced Repolarization of Peritoneal Macrophages Using CD44 Targeting Hyaluronic Acid Nanoparticles for Anti-Inflammatory Effects
por: Tran, Thanh-Huyen, et al.
Publicado: (2016)

WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia
por: Bordin, Fulvio, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_a93r318arot7vi3nqkrh5uqjs7