Viremic long-term nonprogressive HIV-1 infection is not associated with abnormalities in known Nef functions

BACKGROUND: A small minority of HIV-1-infected individuals show low levels of immune activation and do not develop immunodeficiency despite high viral loads. Since the accessory viral Nef protein modulates T cell activation and plays a key role in the pathogenesis of AIDS, we investigated whether sp...

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Detalles Bibliográficos
Autores principales: Heigele, Anke, Camerini, David, van’t Wout, Angélique B, Kirchhoff, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927655/
https://www.ncbi.nlm.nih.gov/pubmed/24495362
http://dx.doi.org/10.1186/1742-4690-11-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927655/
https://www.ncbi.nlm.nih.gov/pubmed/24495362
http://dx.doi.org/10.1186/1742-4690-11-13

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