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Viremic long-term nonprogressive HIV-1 infection is not associated with abnormalities in known Nef functions

BACKGROUND: A small minority of HIV-1-infected individuals show low levels of immune activation and do not develop immunodeficiency despite high viral loads. Since the accessory viral Nef protein modulates T cell activation and plays a key role in the pathogenesis of AIDS, we investigated whether sp...

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Detalles Bibliográficos
Autores principales:	Heigele, Anke, Camerini, David, van’t Wout, Angélique B, Kirchhoff, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927655/ https://www.ncbi.nlm.nih.gov/pubmed/24495362 http://dx.doi.org/10.1186/1742-4690-11-13

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