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Viremic long-term nonprogressive HIV-1 infection is not associated with abnormalities in known Nef functions
BACKGROUND: A small minority of HIV-1-infected individuals show low levels of immune activation and do not develop immunodeficiency despite high viral loads. Since the accessory viral Nef protein modulates T cell activation and plays a key role in the pathogenesis of AIDS, we investigated whether sp...
Autores principales: | Heigele, Anke, Camerini, David, van’t Wout, Angélique B, Kirchhoff, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927655/ https://www.ncbi.nlm.nih.gov/pubmed/24495362 http://dx.doi.org/10.1186/1742-4690-11-13 |
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