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High levels of anti-Nef antibodies may prevent AIDS disease progression in vertically HIV-1-infected infants

INTRODUCTION: HIV-1-associated CD4+ T-cell depletion is a consequence of uninfected cell death. Nef is one of the viral factors that trigger apoptosis on bystander cells, though the plasma Nef levels do not correlate with Th lymphocytes counts. The aim of our study was to evaluate whether anti-Nef a...

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Detalles Bibliográficos
Autores principales: Corró, Guillermo, Crudeli, Cintia Milena, Rocco, Carlos Alberto, Marino, Silvia Alejandra, Sen, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927729/
https://www.ncbi.nlm.nih.gov/pubmed/24560340
http://dx.doi.org/10.7448/IAS.17.1.18790