HO-1 Induction by CO-RM2 Attenuates TNF-α-Induced Cytosolic Phospholipase A(2) Expression via Inhibition of PKCα-Dependent NADPH Oxidase/ROS and NF-κB

Rheumatoid arthritis (RA) is characterized by chronic inflammatory infiltration of the synovium and elevation of proinflammatory cytokines. Cytosolic phospholipase A(2) (cPLA(2)) is involved in the development of inflammatory diseases. Heme oxygenase-1 (HO-1) has been shown to possess anti-inflammat...

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Detalles Bibliográficos
Autores principales: Chi, Pei-Ling, Liu, Chun-Ju, Lee, I-Ta, Chen, Yu-Wen, Hsiao, Li-Der, Yang, Chuen-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927740/
https://www.ncbi.nlm.nih.gov/pubmed/24616552
http://dx.doi.org/10.1155/2014/279171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927740/
https://www.ncbi.nlm.nih.gov/pubmed/24616552
http://dx.doi.org/10.1155/2014/279171

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