Cargando…

HO-1 Induction by CO-RM2 Attenuates TNF-α-Induced Cytosolic Phospholipase A(2) Expression via Inhibition of PKCα-Dependent NADPH Oxidase/ROS and NF-κB

Rheumatoid arthritis (RA) is characterized by chronic inflammatory infiltration of the synovium and elevation of proinflammatory cytokines. Cytosolic phospholipase A(2) (cPLA(2)) is involved in the development of inflammatory diseases. Heme oxygenase-1 (HO-1) has been shown to possess anti-inflammat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chi, Pei-Ling, Liu, Chun-Ju, Lee, I-Ta, Chen, Yu-Wen, Hsiao, Li-Der, Yang, Chuen-Mao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927740/ https://www.ncbi.nlm.nih.gov/pubmed/24616552 http://dx.doi.org/10.1155/2014/279171

Ejemplares similares

NADPH Oxidase/ROS-Dependent VCAM-1 Induction on TNF-α-Challenged Human Cardiac Fibroblasts Enhances Monocyte Adhesion
por: Lin, Chih-Chung, et al.
Publicado: (2016)

Unique targeting of cytosolic phospholipase A(2) to plasma membranes mediated by the NADPH oxidase in phagocytes
por: Shmelzer, Zeev, et al.
Publicado: (2003)

TNF-α Induces Cytosolic Phospholipase A(2) Expression in Human Lung Epithelial Cells via JNK1/2- and p38 MAPK-Dependent AP-1 Activation
por: Lee, I-Ta, et al.
Publicado: (2013)

Nitroglycerine-Induced Nitrate Tolerance Compromises Propofol Protection of the Endothelial Cells against TNF-α: The Role of PKC-β (2) and NADPH Oxidase
por: Lei, Shaoqing, et al.
Publicado: (2013)

Correction: TNF-α Induces Cytosolic Phospholipase A(2) Expression in Human Lung Epithelial Cells via JNK1/2- and p38 MAPK-Dependent AP-1 Activation
por: Lee, I-Ta, et al.
Publicado: (2013)

Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise
por: Henríquez-Olguin, Carlos, et al.
Publicado: (2019)

Adipose afferent reflex is enhanced by TNFα in paraventricular nucleus through NADPH oxidase-dependent ROS generation in obesity-related hypertensive rats
por: Ding, Lei, et al.
Publicado: (2019)

Cigarette smoke extract upregulates heme oxygenase-1 via PKC/NADPH oxidase/ROS/PDGFR/PI3K/Akt pathway in mouse brain endothelial cells
por: Shih, Ruey-Horng, et al.
Publicado: (2011)

Upregulation of COX-2 and PGE(2) Induced by TNF-α Mediated Through TNFR1/MitoROS/PKCα/P38 MAPK, JNK1/2/FoxO1 Cascade in Human Cardiac Fibroblasts
por: Yang, Chuen-Mao, et al.
Publicado: (2021)

Nrf2 regulates ROS production by mitochondria and NADPH oxidase
por: Kovac, Stjepana, et al.
Publicado: (2015)

TNF-α-Induced cPLA(2) Expression via NADPH Oxidase/Reactive Oxygen Species-Dependent NF-κB Cascade on Human Pulmonary Alveolar Epithelial Cells
por: Lin, Chih-Chung, et al.
Publicado: (2016)

Propofol Reduces Lipopolysaccharide-Induced, NADPH Oxidase (NOX(2)) Mediated TNF-α and IL-6 Production in Macrophages
por: Meng, Tao, et al.
Publicado: (2013)

Hu-Lu-Ba-Wan Attenuates Diabetic Nephropathy in Type 2 Diabetic Rats through PKC-α/NADPH Oxidase Signaling Pathway
por: Zhou, Lishan, et al.
Publicado: (2013)

ATP Mediates NADPH Oxidase/ROS Generation and COX-2/PGE(2) Expression in A549 Cells: Role of P2 Receptor-Dependent STAT3 Activation
por: Cheng, Shin-Ei, et al.
Publicado: (2013)

Induction of HO-1 by Mevastatin Mediated via a Nox/ROS-Dependent c-Src/PDGFRα/PI3K/Akt/Nrf2/ARE Cascade Suppresses TNF-α-Induced Lung Inflammation
por: Lin, Chih-Chung, et al.
Publicado: (2020)

Inhibition of Cytosolic Phospholipase A(2)α (cPLA(2)α) by Medicinal Plants in Relation to Their Phenolic Content
por: Arnold, Eva, et al.
Publicado: (2015)

Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis
por: Marusic, Suzana, et al.
Publicado: (2005)

Cytosolic Phospholipase A(2)α–deficient Mice Are Resistant to Collagen-induced Arthritis
por: Hegen, Martin, et al.
Publicado: (2003)

Pharmacophore-based discovery of a novel cytosolic phospholipase A(2)α inhibitor
por: Noha, Stefan M., et al.
Publicado: (2012)

Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells
por: Mahammad, Nur, et al.
Publicado: (2021)

Structural basis of phosphatidylcholine recognition by the C2–domain of cytosolic phospholipase A(2)α
por: Hirano, Yoshinori, et al.
Publicado: (2019)

Discrete Role for Cytosolic Phospholipase A(2)α in Platelets: Studies Using Single and Double Mutant Mice of Cytosolic and Group IIA Secretory Phospholipase A(2)
por: Wong, Dennis A., et al.
Publicado: (2002)

From Flies to Men: ROS and the NADPH Oxidase in Phagocytes
por: Moghadam, Zohreh Mansoori, et al.
Publicado: (2021)

TNF-α Mediates PKCδ/JNK1/2/c-Jun-Dependent Monocyte Adhesion via ICAM-1 Induction in Human Retinal Pigment Epithelial Cells
por: Lee, I-Ta, et al.
Publicado: (2015)

Epicardial Adipose Tissue–Derived Leptin Promotes Myocardial Injury in Metabolic Syndrome Rats Through PKC/NADPH Oxidase/ROS Pathway
por: Chen, Hui, et al.
Publicado: (2023)

Correction: Structural basis of phosphatidylcholine recognition by the C2-Domain of cytosolic phospholipase A(2)α
por: Hirano, Yoshinori, et al.
Publicado: (2021)

Predominant Role of Cytosolic Phospholipase A(2)α in Dioxin-induced Neonatal Hydronephrosis in Mice
por: Yoshioka, Wataru, et al.
Publicado: (2014)

Resveratrol prevents nanoparticles-induced inflammation and oxidative stress via downregulation of PKC-α and NADPH oxidase in lung epithelial A549 cells
por: Hsu, Hung-Te, et al.
Publicado: (2018)

Cytosolic Ca(2+) Modulates Golgi Structure Through PKCα-Mediated GRASP55 Phosphorylation
por: Ireland, Stephen, et al.
Publicado: (2020)

Regulation of ROS signal transduction by NADPH oxidase 4 localization
por: Chen, Kai, et al.
Publicado: (2008)

NADPH oxidase NOX4 is a glycolytic regulator through mROS-HIF1α axis in thyroid carcinomas
por: Tang, Ping, et al.
Publicado: (2018)

HIF-1α-Mediated, NADPH Oxidase-Derived ROS Contributes to Laryngeal Airway Hyperreactivity Induced by Intermittent Hypoxia in Rats
por: Lin, You Shuei, et al.
Publicado: (2020)

Participation of lipopolysaccharide in hyperplasic adipose expansion: Involvement of NADPH oxidase/ROS/p42/p44 MAPK‐dependent Cyclooxygenase‐2
por: Chang, Chao‐Chien, et al.
Publicado: (2022)

tBHQ attenuates podocyte injury in diabetic nephropathy by inhibiting NADPH oxidase-derived ROS generation via the Nrf2/HO-1 signalling pathway
por: Liu, Ting, et al.
Publicado: (2022)

Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils
por: Ohayon, Delphine, et al.
Publicado: (2019)

HIF-1α Activation by Intermittent Hypoxia Requires NADPH Oxidase Stimulation by Xanthine Oxidase
por: Nanduri, Jayasri, et al.
Publicado: (2015)

Cytosolic Phospholipase A2 Regulates TNF-Induced Production of Joint Destructive Effectors in Synoviocytes
por: Sommerfelt, Randi M., et al.
Publicado: (2013)

The Anorexigenic Effect of Serotonin Is Mediated by the Generation of NADPH Oxidase-Dependent ROS
por: Fang, Xin-Ling, et al.
Publicado: (2013)

Correction: Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils
por: Ohayon, Delphine, et al.
Publicado: (2019)

Phospholipase D1 Mediates TNFα-Induced Inflammation in a Murine Model of TNFα-Induced Peritonitis
por: Sethu, Swaminathan, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_nulngnu7suapgf8hq9af7ff7db