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Reconstitution of bone-like matrix in osteogenically differentiated mesenchymal stem cell–collagen constructs: A three-dimensional in vitro model to study hematopoietic stem cell niche

Mesenchymal stem/stromal cells (MSCs) and osteoblasts are important niche cells for hematopoietic stem cells (HSCs) in bone marrow osteoblastic niche. Here, we aim to partially reconstitute the bone marrow HSC niche in vitro using collagen microencapsulation for investigation of the interactions bet...

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Detalles Bibliográficos
Autores principales: Lai, WY, Li, YY, Mak, SK, Ho, FC, Chow, ST, Chooi, WH, Chow, CH, Leung, AY, Chan, BP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927755/
https://www.ncbi.nlm.nih.gov/pubmed/24555007
http://dx.doi.org/10.1177/2041731413508668