Potential for intranasal drug delivery to alter cerebrospinal fluid outflow via the nasal turbinate lymphatics

BACKGROUND: Cerebrospinal fluid absorption (CSF) at the cribriform plate is mediated by direct extracranial connections to the lymphatic system. Given the accessibility of these pharmacologically responsive vessels we hypothesized that the rate of CSF outflow can be modulated via the intranasal deli...

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Detalles Bibliográficos
Autores principales: Kim, Harold, Moore, Sara A, Johnston, Miles G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927830/
https://www.ncbi.nlm.nih.gov/pubmed/24528926
http://dx.doi.org/10.1186/2045-8118-11-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927830/
https://www.ncbi.nlm.nih.gov/pubmed/24528926
http://dx.doi.org/10.1186/2045-8118-11-4

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