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Potential for intranasal drug delivery to alter cerebrospinal fluid outflow via the nasal turbinate lymphatics
BACKGROUND: Cerebrospinal fluid absorption (CSF) at the cribriform plate is mediated by direct extracranial connections to the lymphatic system. Given the accessibility of these pharmacologically responsive vessels we hypothesized that the rate of CSF outflow can be modulated via the intranasal deli...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927830/ https://www.ncbi.nlm.nih.gov/pubmed/24528926 http://dx.doi.org/10.1186/2045-8118-11-4 |