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STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry

Orai1 calcium channels in the plasma membrane are activated by stromal interaction molecule-1 (STIM1), an endoplasmic reticulum calcium sensor, to mediate store-operated calcium entry (SOCE). The cytosolic region of STIM1 contains a long putative coiled-coil (CC)1 segment and shorter CC2 and CC3 dom...

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Detalles Bibliográficos
Autores principales: Stathopulos, Peter B., Schindl, Rainer, Fahrner, Marc, Zheng, Le, Gasmi-Seabrook, Geneviève M., Muik, Martin, Romanin, Christoph, Ikura, Mitsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927877/
https://www.ncbi.nlm.nih.gov/pubmed/24351972
http://dx.doi.org/10.1038/ncomms3963