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Targeting endothelial junctional adhesion molecule-A/ EPAC/ Rap-1 axis as a novel strategy to increase stem cell engraftment in dystrophic muscles

Muscular dystrophies are severe genetic diseases for which no efficacious therapies exist. Experimental clinical treatments include intra-arterial administration of vessel-associated stem cells, called mesoangioblasts (MABs). However, one of the limitations of this approach is the relatively low num...

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Detalles Bibliográficos
Autores principales: Giannotta, Monica, Benedetti, Sara, Tedesco, Francesco Saverio, Corada, Monica, Trani, Marianna, D'Antuono, Rocco, Millet, Queensta, Orsenigo, Fabrizio, Gálvez, Beatriz G, Cossu, Giulio, Dejana, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927958/
https://www.ncbi.nlm.nih.gov/pubmed/24378569
http://dx.doi.org/10.1002/emmm.201302520