ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis

The transmembrane metalloprotease-disintegrin ADAM8 mediates cell adhesion and shedding of ligands, receptors and extracellular matrix components. Here, we report that ADAM8 is abundantly expressed in breast tumors and derived metastases compared to normal tissue, especially in triple-negative breas...

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Detalles Bibliográficos
Autores principales: Romagnoli, Mathilde, Mineva, Nora D, Polmear, Michael, Conrad, Catharina, Srinivasan, Srimathi, Loussouarn, Delphine, Barillé-Nion, Sophie, Georgakoudi, Irene, Dagg, Áine, McDermott, Enda W, Duffy, Michael J, McGowan, Patricia M, Schlomann, Uwe, Parsons, Maddy, Bartsch, Jörg W, Sonenshein, Gail E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927960/
https://www.ncbi.nlm.nih.gov/pubmed/24375628
http://dx.doi.org/10.1002/emmm.201303373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927960/
https://www.ncbi.nlm.nih.gov/pubmed/24375628
http://dx.doi.org/10.1002/emmm.201303373

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