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Reversible and irreversible differentiation of cardiac fibroblasts

AIMS: Differentiation of cardiac fibroblasts (Fbs) into myofibroblasts (MyoFbs) is responsible for connective tissue build-up in myocardial remodelling. We examined MyoFb differentiation and reversibility. METHODS AND RESULTS: Adult rat cardiac Fbs were cultured on a plastic substratum providing mec...

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Detalles Bibliográficos
Autores principales: Driesen, Ronald B., Nagaraju, Chandan K., Abi-Char, Joëlle, Coenen, Tamara, Lijnen, Paul J., Fagard, Robert H., Sipido, Karin R., Petrov, Victor V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928002/
https://www.ncbi.nlm.nih.gov/pubmed/24368833
http://dx.doi.org/10.1093/cvr/cvt338