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Indirubin-3′-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migration

AIMS: The small molecule indirubin-3′-monoxime (I3MO) has been shown to inhibit vascular smooth muscle cell (VSMC) proliferation and neointima formation in vivo. The influence of I3MO on VSMC migration and vascular inflammation, two additional key players during the onset of atherosclerosis and rest...

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Detalles Bibliográficos
Autores principales: Blažević, Tina, Schaible, Anja M., Weinhäupl, Katharina, Schachner, Daniel, Nikels, Felix, Weinigel, Christina, Barz, Dagmar, Atanasov, Atanas G., Pergola, Carlo, Werz, Oliver, Dirsch, Verena M., Heiss, Elke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928003/
https://www.ncbi.nlm.nih.gov/pubmed/24368834
http://dx.doi.org/10.1093/cvr/cvt339