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Cecum Lymph Node Dendritic Cells Harbor Slow-Growing Bacteria Phenotypically Tolerant to Antibiotic Treatment

In vivo, antibiotics are often much less efficient than ex vivo and relapses can occur. The reasons for poor in vivo activity are still not completely understood. We have studied the fluoroquinolone antibiotic ciprofloxacin in an animal model for complicated Salmonellosis. High-dose ciprofloxacin tr...

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Detalles Bibliográficos
Autores principales: Kaiser, Patrick, Regoes, Roland R., Dolowschiak, Tamas, Wotzka, Sandra Y., Lengefeld, Jette, Slack, Emma, Grant, Andrew J., Ackermann, Martin, Hardt, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928039/
https://www.ncbi.nlm.nih.gov/pubmed/24558351
http://dx.doi.org/10.1371/journal.pbio.1001793