Molecular Dynamics Simulations of the Cardiac Troponin Complex Performed with FRET Distances as Restraints

Cardiac troponin (cTn) is the Ca(2+)-sensitive molecular switch that controls cardiac muscle activation and relaxation. However, the molecular detail of the switching mechanism and how the Ca(2+) signal received at cardiac troponin C (cTnC) is communicated to cardiac troponin I (cTnI) are still elus...

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Detalles Bibliográficos
Autores principales: Jayasundar, Jayant James, Xing, Jun, Robinson, John M., Cheung, Herbert C., Dong, Wen-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928104/
https://www.ncbi.nlm.nih.gov/pubmed/24558365
http://dx.doi.org/10.1371/journal.pone.0087135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928104/
https://www.ncbi.nlm.nih.gov/pubmed/24558365
http://dx.doi.org/10.1371/journal.pone.0087135

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