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Molecular Dynamics Simulations of the Cardiac Troponin Complex Performed with FRET Distances as Restraints
Cardiac troponin (cTn) is the Ca(2+)-sensitive molecular switch that controls cardiac muscle activation and relaxation. However, the molecular detail of the switching mechanism and how the Ca(2+) signal received at cardiac troponin C (cTnC) is communicated to cardiac troponin I (cTnI) are still elus...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928104/ https://www.ncbi.nlm.nih.gov/pubmed/24558365 http://dx.doi.org/10.1371/journal.pone.0087135 |