Organophosphate-Induced Changes in the PKA Regulatory Function of Swiss Cheese/NTE Lead to Behavioral Deficits and Neurodegeneration

Organophosphate-induced delayed neuropathy (OPIDN) is a Wallerian-type axonopathy that occurs weeks after exposure to certain organophosphates (OPs). OPs have been shown to bind to Neuropathy Target Esterase (NTE), thereby inhibiting its enzymatic activity. However, only OPs that also induce the so-...

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Detalles Bibliográficos
Autores principales: Wentzell, Jill S., Cassar, Marlène, Kretzschmar, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928115/
https://www.ncbi.nlm.nih.gov/pubmed/24558370
http://dx.doi.org/10.1371/journal.pone.0087526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928115/
https://www.ncbi.nlm.nih.gov/pubmed/24558370
http://dx.doi.org/10.1371/journal.pone.0087526

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