The effect of CD14 and TLR4 gene polimorphisms on asthma phenotypes in adult Turkish asthma patients: a genetic study

BACKGROUND: Endotoxins stimulate T helper 1 cell maturation and send a negative signal to T helper 2 polarisation. This causes a decrease IgE levels and prevents atopy (Hygiene hypothesis). It is shown that this response is under genetic control by polymorphisms in CD14 and TLR4 genes in some resear...

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Detalles Bibliográficos
Autores principales: Şahin, Füsun, Yıldız, Pınar, Kuskucu, Ayşegül, Kuskucu, Mert Ahmet, Karaca, Nilgün, Midilli, Kenan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928321/
https://www.ncbi.nlm.nih.gov/pubmed/24524443
http://dx.doi.org/10.1186/1471-2466-14-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928321/
https://www.ncbi.nlm.nih.gov/pubmed/24524443
http://dx.doi.org/10.1186/1471-2466-14-20

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