Cargando…

Glibenclamide Decreases ATP-Induced Intracellular Calcium Transient Elevation via Inhibiting Reactive Oxygen Species and Mitochondrial Activity in Macrophages

Increasing evidence has revealed that glibenclamide has a wide range of anti-inflammatory effects. However, it is unclear whether glibenclamide can affect the resting and adenosine triphosphate (ATP)-induced intracellular calcium ([Ca(2+)](i)) handling in Raw 264.7 macrophages. In the present study,...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Duo-ling, Ma, Zhi-yong, Fu, Zhi-jie, Ling, Ming-ying, Yan, Chuan-zhu, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928368/
https://www.ncbi.nlm.nih.gov/pubmed/24558474
http://dx.doi.org/10.1371/journal.pone.0089083